If you are planning a trip to the second-largest city in the Czech Republic, finding the right Prague-Brno and back transportation is highly important. Because Brno sits right between major European hubs, figuring out how to go to Brno is simple once you know the best routes.
Travel Comparison: Prague to Brno and Back
| Transport | Trip Length | Estimated Cost | Reliability |
| Train | 2h 30m – 3h | 150 – 450 CZK | High (Highly recommended) |
| Bus | 2h 30m – 5h+ | 150 – 350 CZK | Low (D1 highway is often blocked) |
Before you choose how to travel, you can read our deep breakdown comparing prices, comfort, and speed in our article Train vs Bus in Czechia: What is the Best?.
🚂 Prague to Brno by Train
Taking a Praha-Brno train is the most popular, comfortable, and reliable option for travelers. Trains leave every single hour from Prague Main Station (Praha hlavní nádraží) and arrive directly at Brno Main Station (Brno hlavní nádraží).
- Travel Time: Around 2.5 hours.
- The Main Providers: You can choose between the national rail company (České dráhy) or a private company like RegioJet.
- The RegioJet Benefit: Booking a Brno to Prague RegioJet train is highly popular because they give you free perks. You get free Wi-Fi, free bottled water, and free coffee throughout the whole trip. They also have a famous onboard menu with incredibly cheap snacks. You can buy delicious traditional Czech sweet pastries (koláče with apple or plum) for just 10 CZK, or a ham and cheese croissant for around 25 to 35 CZK. The food is fresh, cheap, and perfect for a quick breakfast.
Tip for Mobile Users: download the official carrier apps to buy your tickets online in advance. Trains can get fully booked during weekends. For a complete list of helpful travel tools on your phone, see our guide to the Useful Apps for Tourists in Prague and ČR.
⏱️Weekday morning trains Prague-Brno timetable
| Departure (Prague) | Arrival (Brno) | Travel Time | Train Operator & Type |
| 06:37 | 09:13 | 2h 36m | ČD (Railjet “Vindobona”) |
| 07:01 | 09:40 | 2h 39m | RegioJet (Yellow Train) |
| 07:37 | 10:13 | 2h 36m | ČD (Railjet “Metropolitan”) |
| 08:37 | 11:13 | 2h 36m | ČD (Railjet “Vindobona”) |
| 09:01 | 11:40 | 2h 39m | RegioJet (Yellow Train) |
| 09:37 | 12:13 | 2h 36m | ČD (Railjet “Metropolitan”) |
| 11:01 | 13:40 | 2h 39m | RegioJet (Yellow Train) |
| 11:37 | 14:13 | 2h 36m | ČD (EuroCity “Metropolitan”) |
Note for Readers: This is a typical weekday morning timetable. Exact times can change slightly during national holidays or track maintenance. Always do a quick final check on the Idos.cz app before you go!
🚌 Prague to Brno by Bus
If you prefer traveling by road, you can easily book a Prague to Brno bus (or back). Buses depart from the Prague Florenc bus station.
- Travel Time: 2.5 to 3.5 hours.
- Main Brands: You will mostly find options for RegioJet and FlixBus. Both runs multiple times a day.
⚠️ Road Traffic Warning: Unlike the train, buses must use the busy D1 highway. This road is famous for sudden traffic jams and delays. If you have a flight to catch or a tight schedule, avoid the bus and take the train.
⏱️ Prague to Brno: Morning Bus Schedule
Most direct intercity buses leave from the Prague Florenc Bus Station (Praha, ÚAN Florenc) and arrive at either the Brno Grand Hotel station or the Brno Zvonařka Central Bus Station.
| Departure (Prague) | Arrival (Brno) | Travel Time | Bus Operator |
| 06:30 | 09:10 | 2h 40m | FlixBus |
| 07:00 | 09:30 | 2h 30m | RegioJet |
| 08:00 | 10:55 | 2h 55m | RegioJet |
| 08:05 | 11:00 | 2h 55m | FlixBus |
| 09:00 | 11:20 | 2h 20m | FlixBus |
| 09:00 | 11:25 | 2h 25m | RegioJet |
| 09:30 | 12:00 | 2h 30m | RegioJet |
| 10:00 | 12:55 | 2h 55m | RegioJet |
| 10:05 | 12:40 | 2h 35m | FlixBus |
⚠️ Important Reminder for Your Readers: Travel times for buses can change drastically depending on traffic conditions on the D1 highway. Always remind your readers to plan for potential delays if they choose the bus!
✈️ Traveling From Prague Airport to Brno
f you land at Prague Airport (Václav Havel Airport), there is no direct train station inside the building. To get from Prague airport to Brno, you have two main routes:
Route 1: Travel via Prague Main Station (Best for Train Connections)
Most travelers go from the airport to Prague Main Station (Hlavní nádraží) first, and then take the comfortable 2.5-hour train to Brno. Here are the two ways to reach the train station:
- The Absolute Cheapest Way (Local Transit): If you are on a budget, buy a 90-minute city transport ticket for 46 CZK (on the Lítačka app) or 50 CZK (paper ticket). Take Trolleybus 59 from outside the terminal to the Nádraží Veleslavín metro station. Jump on Metro Line A (Green), change to Line C (Red) at Muzeum, and get off at the Main Station. To make sure you buy the right ticket and don’t get a penalty from inspectors, read How to Use Prague Public Transport Without Mistakes and Fine.
- The Smart “Group Trick” (Taxi vs. AE Bus): The airport has a direct Airport Express (AE) bus to the train station, but it costs 200 CZK per adult. If you are traveling as a couple or a small group, do not take the AE bus. For two or more people, a ride-hailing app like Bolt or Uber will cost almost the same money (or less) and save you a lot of hassle. You can check the current prices in our guide How to Get a Prague Airport Taxi: Uber, Bolt, and Local Rates. To stay safe from dishonest drivers also check out Prague Taxi Scams: The Safest Way in 2026.
Route 2: Direct Intercity Buses (No Transfers)
- You can book a direct Bus from Prague airport to Brno or a Brno to Prague airport via RegioJet or FlixBus. These buses pick you up directly outside the airport terminals. This is a great choice if you do not want to carry your luggage between buses and metros, but keep in mind that these direct buses run much less frequently than the city trains.
Landing late at night? If your flight arrives after the metro and daytime buses close, the transit routes to the train station change. Read our guide on Prague Airport Night Transport: How It Work After Midnight to plan your late arrival.
🇦🇹 The Vienna Airport Hack
Many tourists do not realize that Brno is actually closer to Vienna (Austria) than it is to Prague! If you are looking for the fastest route, check out how to get from Vienna airport to Brno.
- Direct buses run 24/7 right from the Vienna Airport arrivals terminal straight to Brno city center.
- The bus ride takes only 2 hours, making it faster and easier than arriving via Prague Airport.
- Where to book: You can check live schedules, view seat maps, and buy tickets directly on the official RegioJet website or via the FlixBus online portal.
⏱️ Vienna Airport to Brno: Morning Bus Schedule
Buses pick you up directly outside the arrivals terminal at Vienna Airport (Platform 3 or 4) and drop you off in the center of Brno (usually at Brno Grand Hotel or Benešova station).
| Departure (Vienna Airport) | Arrival (Brno) | Travel Time | Operator | Average Price (Approx.) |
| 06:10 | 08:50 | 2h 40m | RegioJet | 310 CZK (€12) |
| 06:45 | 08:55 | 2h 10m | FlixBus | 360 CZK (€14) |
| 07:10 | 09:50 | 2h 40m | RegioJet | 410 CZK (€16) |
| 08:15 | 10:55 | 2h 40m | RegioJet | 310 CZK (€12) |
| 08:25 | 10:50 | 2h 25m | FlixBus | 390 CZK (€15) |
| 10:10 | 12:00 | 1h 50m | RegioJet | 310 CZK (€12) |
| 10:20 | 12:25 | 2h 05m | FlixBus | 360 CZK (€14) |
| 11:10 | 13:50 | 2h 40m | RegioJet | 410 CZK (€16) |
| 12:40 | 15:00 | 2h 20m | FlixBus | 490 CZK (€20) |
Insider Note for Readers: Prices on this route fluctuate based on how early you book and how full the bus is. Booking a few days in advance via the RegioJet or FlixBus apps ensures you lock in the lowest €12–15 rates.
🇬🇧 How to Get to Brno from the UK
If you are wondering how to get to Brno from UK, you have:
- Direct Flights: You do not have to fly into Prague. Ryanair operates direct flights from London Stansted (STN) straight to Brno-Tuřany Airport (BRQ). The flight takes just about 2 hours.
- Alternative Route: If you fly from other UK airports (like Manchester, Edinburgh, or London Heathrow), you can catch a flight to Vienna Airport or Prague Airport, and then use the bus or train links mentioned above.
